消化性溃疡(PU)的发病是胃内两种因素失去平衡,即侵袭因素(盐酸和胃蛋白酶)增强,抵御因素(胃粘膜屏障等)减弱的结果,因此,治疗的原则在于纠正上述不平衡状态。常用药物;(1)抑制侵袭因素:①中和胃酸:制酸剂。②抑制酸分泌:抗胆碱能药物(哌吡氮平、Telezepine),H_2受体阻滞剂(甲氰眯胍、呋喃硝胺、Famotidine、Nizatidine),H~+- The pathogenesis of peptic ulcer (PU) is the result of imbalance of two factors in the stomach, that is, the enhancement of invasion factors (hydrochloric acid and pepsin) and the weakened resistance factors (gastric mucosal barrier). Therefore, the principle of treatment is to correct the above imbalance status. Commonly used drugs; (1) inhibition of invasion factors: ① and stomach acid: antacids. ② Inhibition of acid secretion: anticholinergic drugs (Telezepine), H 2 blockers (Famotidine, Nizatidine), H ~ + -