目的:探讨白三烯受体拮抗药孟鲁司特对小儿轻、中度哮喘的疗效。方法:将80例患者随机分为观察组46例,对照组34例,哮喘发作时对照组单纯吸入倍氯米松,观察组在吸入倍氯米松的基础上加口服孟鲁司特2～4周,比较两组疗效。结果:治疗半年内观察组吸入倍氯米松剂量减少,效果优于对照组(P<0.05)。结论:小儿轻、中度哮喘患儿应用肾上腺皮质激素(激素)的基础上加用孟鲁司特可提高其疗效,并有助于减少激素吸入剂量。 Objective: To investigate the effect of leukotriene receptor antagonist Montelukast on children with mild to moderate asthma. Methods: Eighty patients were randomly divided into observation group (n = 46) and control group (n = 34). The control group received only beclomethasone during the asthma attack. The observation group was given inhaled beclomethasone for 2 to 4 weeks , Compare the two groups curative effect. Results: The dose of beclomethasone inhaled in the observation group decreased within six months, which was better than that of the control group (P <0.05). CONCLUSION: Montelukast can improve the curative effect of adrenal cortical hormone (hormone) in children with mild and moderate asthma, and help to reduce the dose of hormone inhalation.