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目的 评价成年癫痫患者的生活质量。方法 对符合入选标准的 33例成年癫痫患者和正常对照者 17名 ,进行癫痫患者生活质量量表 31(QOLIE 31)、Zung氏抑郁自评表 (SDS)的评估。结果 SDS评分水平与QOL的多个方面呈独立负相关 ,病程是总体健康水平、药物影响的独立危险因素。全身强直 阵挛发作 (GTC ,17例 )、复杂部分性发作 (CPS ,16例 )两组患者在药物影响 (分别为 6 1 0± 2 3 8和 5 6 6± 19 4,对照组为 10 0± 0 0 )、对发作的担忧两方面均与对照组有显著性差异 (P <0 .0 0 1)。GTC组从事脑力劳动的人数大大低于学历背景相似的对照组 (P =0 0 1) ,而CPS组从事脑力劳动的人数与对照组相比差异无显著性意义 (P =0 .479) ,GTC组与CPS组相比未见显著性差异 (P =0 .0 97)。男性癫痫患者在婚育方面受到的影响有大于女性患者的趋势。结论 成年癫痫患者生活质量低于健康对照组。
Objective To evaluate the quality of life in adults with epilepsy. Methods Totally 33 adults with epilepsy and 17 normal controls were enrolled in the study. QOLIE 31 and Zung Self-Rating Depression Scale (SDS) were evaluated. Results There was an independent negative correlation between SDS score and various aspects of QOL. The course of disease was an independent risk factor of overall health and drug influence. Twenty-four patients with systemic tonic-clonic seizures (GTC, 17 patients) and complex partial seizures (CPS, 16 patients) were affected by the drug (6 1 0 ± 2 3 8 and 5 6 6 ± 19 4, respectively, and control group 10 0 ± 0 0). There was a significant difference between the two groups in the onset of symptoms (P <0.01). The number of mental workers in the GTC group was significantly lower than that of the control group with similar education background (P = 0 0 1), but there was no significant difference between the CPS group and the control group (P = 0. 479) There was no significant difference between GTC group and CPS group (P = 0.097). Male patients with epilepsy in marriage and childbearing have been affected more than female patients trend. Conclusion The quality of life of adults with epilepsy is lower than that of healthy controls.