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目的探讨急性细菌性痢疾菌株药敏分布和临床治疗方法。方法对80例急性细菌性痢疾住院患者的临床资料进行回顾性分析,并分析患者急性细菌性痢疾菌株药敏分布情况以及药敏测试结果与临床治疗的指导作用。结果 80例患者中共检测出51例阳性,患者粪便阳性率为63.75%。菌株均以痢疾志贺菌为主,共39株,占76.47%。福氏菌、鲍氏菌、宋内氏菌较少。病原菌分布情况比较稳定,未出现显著变化。急性细菌性痢疾菌株药敏试验结果显示,耐药明显的为青霉素类药物,耐药率为62.5%,环丙沙星、头孢类耐药性逐年上升(2013年分别为51.0%、22.0%,2014年分别为54.0%、27.0%),其中头孢他啶具有显著的敏感性。结论急性细菌性痢疾菌株药敏分布中最主要的是痢疾志贺菌,环丙沙星、头孢类耐药性逐年上升,依据试验结果对患者采取针对性的治疗措施,可降低耐药性的发生率,提高患者的治愈率。
Objective To investigate the drug sensitivity distribution and clinical treatment of acute bacterial dysentery strains. Methods The clinical data of 80 patients with acute bacillary dysentery were retrospectively analyzed. The distribution of drug susceptibility in patients with acute bacterial dysentery and the guidance of drug sensitivity test results and clinical treatment were analyzed. Results A total of 51 positive cases were detected in 80 cases and the positive rate of feces was 63.75%. Shigella dysentery strains are based, a total of 39, accounting for 76.47%. Forsythia, Brucella, less Song Nei bacteria. Distribution of pathogens is relatively stable, no significant changes. The drug sensitive test results of acute bacillary dysentery strains showed that the drug resistance was obviously penicillin, the drug resistance rate was 62.5%, the drug resistance of ciprofloxacin and cephalosporin increased year by year (51.0% and 22.0% in 2013, 54.0% and 27.0% respectively in 2014), of which ceftazidime has significant sensitivity. Conclusion The main drug sensitivity distribution of acute bacillary dysentery strains is Shigella dysenteriae. The drug resistance of ciprofloxacin and cephalosporin is increasing year by year. According to the test results, the targeted treatment measures can be taken to reduce the drug resistance The incidence, improve the patient’s cure rate.