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Organ-oriented research platform is based on machineperfusion (MP) technology providing continuous oxygenand nutrient supply for harvested organs. It permitsin vivo and in vitro investigation and represents one of thelatest innovations in the quest for a model to explore eitherphysiological or pathological processes of the whole organ.Recently, the ex vivo animal perfusion model has provento be an effective and reproducible translational researchplatform (1).