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雌马酚是大豆异黄酮重要的代谢产物,人群中约有30%～50%的人能将大豆异黄酮转化成雌马酚进而排泄,但影响其转化的因素目前尚不完全清楚,其中肠道菌群可能是最重要的因素。雌马酚较其原型大豆异黄酮具有更为有效的生物学作用。研究并开发雌马酚的生物活性、代谢转化的规律及其生理功能,对于预防和控制心血管病、骨质疏松症、血脂异常、肥胖、更年期综合症以及乳腺癌、前列腺癌等许多慢性疾病具有十分重要的意义。本文就雌马酚在人体内的代谢过程、生物活性以及对于多种慢性病的预防作用做一综述。
Equol is an important metabolite of soy isoflavones, about 30% to 50% of the population of people can be converted into equol and excretion of soy isoflavones, but the factors that affect its conversion is not yet fully understood, which the intestine Road flora may be the most important factor. Equol than its prototype soy isoflavones have a more effective biological role. Research and development of the bioactivity of equol, the law of metabolic conversion and its physiological function, for the prevention and control of cardiovascular diseases, osteoporosis, dyslipidemia, obesity, menopausal syndrome and breast cancer, prostate cancer and many other chronic diseases It is of great significance. This article reviews the metabolic processes, bioactivities of equol in the human body and the preventive effects on various chronic diseases.