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目的 探讨拉莫三嗪治疗中老年癫痫合并抑郁症患者的临床效果.方法 68例中老年癫痫合并抑郁症患者,根据治疗方案不同分为常规组和研究组,各34例.常规组患者应用托吡酯治疗,研究组患者在常规组基础上加入拉莫三嗪治疗.比较两组患者治疗效果及治疗前后癫痫发病次数、抑郁评分.结果 研究组治疗总有效率为94.12％,高于常规组的76.47％,差异有统计学意义(P<0.05).治疗3、6、12个月,研究组癫痫发病次数分别为(5.56±1.03)、(3.87±0.68)、(1.67±0.24)次,均少于常规组的(6.41±
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目的 探讨拉莫三嗪治疗中老年癫痫合并抑郁症患者的临床效果.方法 68例中老年癫痫合并抑郁症患者,根据治疗方案不同分为常规组和研究组,各34例.常规组患者应用托吡酯治疗,研究组患者在常规组基础上加入拉莫三嗪治疗.比较两组患者治疗效果及治疗前后癫痫发病次数、抑郁评分.结果 研究组治疗总有效率为94.12％,高于常规组的76.47％,差异有统计学意义(P<0.05).治疗3、6、12个月,研究组癫痫发病次数分别为(5.56±1.03)、(3.87±0.68)、(1.67±0.24)次,均少于常规组的(6.41±1.00)、(4.22±0.54)、(2.18±0.36)次,差异有统计学意义(P<0.05).治疗后,研究组PHQ-9抑郁症筛查量表评分(13.02±0.88)分低于常规组的(16.16±1.05)分,差异有统计学意义(P<0.05).结论 对中老年癫痫合并抑郁症患者应用拉莫三嗪治疗,其效果显著,可有效改善临床症状及发病次数,值得推广.
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