论文部分内容阅读
循证医学证明,急性心肌梗死早期应用他汀类药物治疗可以获益;小样本试验认为小剂量他汀类药物治疗慢性心力衰竭(CHF)有益,而大剂量治疗没有获益。尽管他汀类药物具有多效性的药理作用,由于CHF患者低TC水平具有不良的预后,应用他汀类药物治疗CHF存在潜在风险〔1〕。他汀类药物能
Evidence-based medicine has shown that early application of statins in acute myocardial infarction may benefit; small sample trials suggest that small doses of statins may be beneficial in the treatment of chronic heart failure (CHF), whereas high-dose therapy does not. Despite the pleiotropic pharmacological effects of statins, there is a potential risk of using statins for the treatment of CHF due to the poor prognosis of low TC levels in CHF patients [1]. Statins can