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[目的]了解高校教职工高尿酸血症患病情况,以及高尿酸血症与质量指数(BMI)、腰围、血压、血脂、血糖的关系,为针对性的健康教育提供依据。[方法]对某高校3635名教职工进行健康体检。内容:问卷调查、查体和实验室检查。问卷调查包括:一般情况、既往病史及吸烟、饮酒、锻炼等情况。查体包括:身高、体重、腰围和血压等。实验室检查有:空腹血糖(FBG)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、肌酐(Cr)和血尿酸等。[结果]参加体检的3635名教职工中,血尿酸水平增高者740人(占20.36%),男性检出率明显高于女性,差异有统计学意义(P<0.05)。高尿酸血症的发生率随年龄的增长而增加。高尿酸血症组的血压、TG、TC、LDL-C)、BMI、腰围、FBG明显高于尿酸正常组,差异有统计学意义(P<0.005)。Logistic回归分析结果显示:男性、超重或肥胖、有高血压病史、TG高、TC高、HDL-C低及Cr升高为高尿酸血症的危险因素(OR分别为1.295、2.607、1.314、1.425、1.461、1.396、2.543)。[结论]该校教职工高尿酸血症检出率较高,提示高校医院应加强高尿酸血症的防治。
[Objective] To understand the prevalence of hyperuricemia and the relationship between hyperuricemia and quality index (BMI), waist circumference, blood pressure, blood lipids and blood glucose in higher education institutions and to provide the basis for targeted health education. [Methods] 3635 faculty and staff in a certain university were given physical examination. Content: Questionnaire, physical examination and laboratory examination. Questionnaires include: general situation, past medical history and smoking, drinking, exercise and so on. Physical examination include: height, weight, waist circumference and blood pressure. Laboratory tests included fasting blood glucose (FBG), total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), creatinine (Cr) And blood uric acid and so on. [Results] Of the 3 635 faculty members attending the medical examination, 740 (20.36%) had higher levels of serum uric acid. The detection rate of males was significantly higher than that of females (P <0.05). The incidence of hyperuricemia increases with age. The blood pressure, TG, TC, LDL-C, BMI, waist circumference and FBG in hyperuricemia group were significantly higher than those in normal uric acid group (P <0.005). Logistic regression analysis showed that men, overweight or obesity, history of hypertension, high TG, high TC, low HDL-C and elevated Cr were the risk factors of hyperuricemia (OR = 1.295,2.607,1.314,1.425 , 1.461, 1.396, 2.543). [Conclusion] The higher detection rate of hyperuricemia among faculty members in colleges and universities suggests that colleges and universities should strengthen the prevention and treatment of hyperuricemia.