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目的探讨1,5-脱水葡萄糖醇(1,5-AG)与T2DM患者UAlb水平相关性。方法选取住院T2DM患者411例,根据HbA1c水平分为≤7%组81例和>7%组330例,另根据24hUAlb将两组各分为<30mg/24h亚组及30~299mg/24h亚组,检测相关生化指标及1,5-AG水平。结果在HbA1c≤7%组中,UAlb 30~299 mg/24h亚组1,5-AG低于UAlb<30 mg/24h亚组[17.3(12.34,23.83)vs 10.40(7.20,13.78)μg/ml,P<0.05];在HbA1c>7%组中,两亚组1,5-AG水平比较,差异无统计学意义[2.67(1.26,6.35)vs 2.44(1.22,5.30)μg/ml,P>0.05]。结论在HbA1c≤7%的T2DM患者中,1,5-AG可能是UAlb水平的相关因素。
Objective To investigate the correlation between 1,5-anhydroglucitol (1,5-AG) and UAlb level in T2DM patients. Methods 411 hospitalized patients with T2DM were enrolled. According to the level of HbA1c, 81 patients were divided into 7 cases and 7 cases, and 330 cases were divided into 30mg / 24h subgroup and 30 ~ 299mg / 24h subgroup according to 24hUAlb , Detection of biochemical indicators and 1,5-AG levels. Results In the HbA1c≤7% group, the 1,5-AG in the UAlb 30 ~ 299 mg / 24h subgroup was lower than that in the UAlb <30 mg / 24h subgroup [17.3 (12.34,23.83) vs 10.40 (7.20,13.78) μg / ml , P <0.05]. In HbA1c> 7% group, there was no significant difference between the two subgroups in the level of 1,5-AG [2.67 (1.26,6.35) vs 2.44 (1.22,5.30) μg / ml, P> 0.05]. Conclusions 1,5-AG may be the related factor of UAlb level in T2DM patients with HbA1c≤7%.