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目的观察昆脂愈肤灵治疗糖尿病足的临床疗效。方法选取69例糖尿病足患者,均为2型糖尿病。将患者随机分为两组:昆脂愈肤灵组(35例)和对照组(34例)。除了控制血糖、抗生素控制感染、支持治疗、纠正贫血和低蛋白血症、创面常规治疗外,昆脂愈肤灵组还用昆脂愈肤灵敷于创面,对照组还用无菌纱布贴敷于创面。观察治疗前后两组患者的血糖水平及创面愈合情况。结果治疗后两组患者血糖水平均较治疗前显著降低(P<0.05),但组间差异无统计学意义(P>0.05)。治疗后昆脂愈肤灵组患者溃疡面愈合时间〔(41.2±2.6)d〕较对照组〔(56.1±2.8)d〕显著缩短,差异有统计学意义(P<0.05);且治疗后昆脂愈肤灵组的有效率(100.0%)显著高于对照组(85.3%),差异有统计学意义(P<0.05)。结论昆脂愈肤灵联用胰岛素强化治疗糖尿病足可加速创面早日愈合,缩短病程,为糖尿病足的内科治疗提供了一种可行性治疗方法。
Objective To observe the curative effect of Kunzhi Yuelianling on diabetic foot. Methods Sixty-nine patients with diabetic foot were selected, all of whom had type 2 diabetes. The patients were randomly divided into two groups: Kunzhiyouling group (35 cases) and control group (34 cases). In addition to controlling blood sugar, antibiotics to control infection, supportive treatment, correct anemia and hypoproteinemia, wound conventional treatment, the Kunju Yueling group also Kun Fu Ya skin lotion in the wound, the control group also with sterile gauze sticking In the wound. The blood sugar level and wound healing of the two groups before and after treatment were observed. Results After treatment, the blood glucose levels in both groups were significantly lower than those before treatment (P <0.05), but there was no significant difference between the two groups (P> 0.05). Compared with the control group [(56.1 ± 2.8) d], the healing time of Kunming Yuelian Ling group was significantly shorter than that of the control group [(41.2 ± 2.6) d], and the difference was statistically significant (P0.05) The effective rate (100.0%) of Zhiyoulingling group was significantly higher than that of control group (85.3%), the difference was statistically significant (P <0.05). Conclusions The treatment of Diabetes Mellitus with Kunziyoulingling combined with insulin can accelerate the wound healing and shorten the course of wound healing, which provides a feasible method for the medical treatment of diabetic foot.