食管静脉出血是门脉高压的一种严重并发症。虽经专业人员的积极治疗,近期死亡率仍高达30%。曾报道静注胃复安可增加食管下部括约肌压力,从而有效地控制急性食管静脉出血。作者用随机双盲安慰剂对照研究来作前瞻性试验。将患者随机分为胃复安20mg 静脉注射或用5%葡萄糖水组。 Esophageal venous hemorrhage is a serious complication of portal hypertension. Despite the active treatment by professionals, the recent death rate is still as high as 30%. It has been reported intravenous metformin can increase the lower esophageal sphincter pressure, thus effectively controlling acute esophageal venous bleeding. The authors used a randomized double-blind placebo-controlled study for prospective trials. The patients were randomly divided into metoclopramide 20mg intravenous injection or 5% glucose water group.