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目的探讨鱼胆中毒的临床表现及血液灌流(HP)串联血液透析抢救重度鱼胆中毒的疗效。方法鱼胆中毒患者29例,入院后除行常规治疗外,均采用血液透析串联HP治疗方法。结果全组患者27例治愈,2例中途退出治疗死亡,治愈率达93.10%。结论血液透析可清除小分子毒素改善肾功能,HP有吸附功能,可清除中大分子毒素,达到解毒作用,血液透析联合HP治疗重度鱼胆中毒患者,疗效确切,为理想的治疗方法。
Objective To investigate the clinical manifestations of fish poisoning and the therapeutic effect of hemoperfusion (HP) in series on hemodialysis for severe fish gall bladder poisoning. Methods Twenty-nine patients with fish gall intoxication were treated with hemodialysis in series except conventional treatment. Results All the patients were cured in 27 cases, and 2 patients died in the middle of the treatment. The cure rate was 93.10%. Conclusion Hemodialysis can remove small molecule toxins and improve renal function. HP has adsorptive function, which can remove middle molecular toxins and achieve detoxification. Hemodialysis combined with HP in patients with severe fish gall bladder poisoning has definite curative effect and is an ideal treatment.