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目的:了解铜仁地区HIV感染者/病人的CD4+T淋巴细胞的免疫水平,为及时进行抗病毒治疗提供依据。方法:采用流式细胞仪(FACS Calibar)对559例HIV感染者/病人进行CD4+T淋巴细胞绝对值检测。结果:559例HIV感染者的CD+4T淋巴细胞均值为303.46±212.90个/μl,CD4+T淋巴细胞计数≤200个/μl的占33.09%,201~350个/μl的占30.23%,351~500个/μl的占21.47%,>500个/μl的占15.21%。不同性别、感染途径的HIV感染者CD4+T淋巴细胞均值的差异无统计学意义,不同年龄的HIV感染者CD4+T淋巴细胞均值的差异有统计学意义。结论:铜仁地区HIV感染者的CD4+T淋巴细胞免疫水平普遍偏低,大部分感染者已进入艾滋病中、晚期。
Objective: To understand the immune status of CD4 + T lymphocytes in HIV-infected patients in Tongren area, and to provide a basis for timely anti-virus therapy. Methods: The absolute value of CD4 + T lymphocytes in 559 HIV-infected patients was detected by flow cytometry (FACS Calibar). Results: The average CD + 4T lymphocyte count was 303.46 ± 212.90 / μl in 559 HIV-infected patients, 33.09% in CD4 + T lymphocyte count ≤ 200 cells / μl, 30.23% in 201-350 cells / μl, 21.47% for ~ 500 / μl and 15.21% for> 500 / μl. The mean of CD4 + T lymphocytes in HIV-infected persons of different genders and routes of infection was not significantly different. The mean of CD4 + T lymphocytes in HIV-infected persons of different ages was statistically significant. Conclusion: The CD4 + T lymphocyte immunity of HIV-infected people in Tongren area is generally low, and most of the infected people have entered the middle and late stages of AIDS.