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目的:探讨CTCAE(常见不良事件评价标准Common Terminology Criteria for Adverse Events)3.0版中血糖异常评价标准在支气管哮喘治疗中的应用。方法:根据CTCAE3.0评价全身应用糖皮质激素治疗支气管哮喘者的血糖异常。结果:糖皮质激素治疗支气管哮喘52例,7例(13.46%)发生空腹血糖升高,无低血糖发生。影响患者空腹血糖升高的因素有糖皮质激素的剂量,BMI和年龄。经过1 a(4~12个月,中位时间5.5个月)随访,证实有1例发生糖尿病。结论:CTCAE 3.0版可方便的应用于支气管哮喘治疗中血糖的评价。
Objective: To investigate the application of CTCAE (Common Terminology Criteria for Adverse Events) 3.0 in the assessment of glycemic abnormality in the treatment of bronchial asthma. Methods: According to CTCAE3.0 evaluation of systemic glucocorticoid treatment of bronchial asthma blood glucose abnormalities. Results: Fifty-two patients with bronchial asthma were treated with glucocorticoid, and fasting blood glucose was increased in seven patients (13.46%) without hypoglycemia. Factors that affect the fasting blood glucose in patients with glucocorticoid dose, BMI and age. After 1 year (4 to 12 months, median 5.5 months) follow-up, confirmed that 1 case of diabetes. Conclusion: CTCAE version 3.0 can be conveniently applied to the evaluation of blood glucose in the treatment of bronchial asthma.