免疫调节剂治疗转移肾细胞癌的大多试验缺少对照比较，以致结果判定易有偏差。本研究设计双盲、安慰剂对照试验，比较重组人干扰素ｒ－１ｂ或安慰剂治疗转移肾细胞癌的总反应率、疾病发展时间以及存活结果。方法经活检证实的转移肾细胞癌患者随机设计为干扰素ｒ－１ｂ组治... Immunomodulatory agents for the treatment of metastatic renal cell carcinoma most of the lack of comparison of the control, resulting in easy to determine the results deviation. This study designed a double-blind, placebo-controlled trial comparing the overall response rates, disease progression, and survival outcomes of recombinant human interferon r-1b or placebo for metastatic renal cell carcinoma. Methods The patients with metastatic renal cell carcinoma confirmed by biopsy were randomly assigned to treat interferon r-1b group ...