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分析42例慢性肾功能不全(CRF)伴高血压患者平均每月血肌酐(Scr)上升和平均每月内生肌酐清除率(Ccr)下降速度;进入终末期肾病(ESRD)的平均时间和需转透析治疗的百分比。结果表明:血压控制不良患者平均每月Scr上升和Ccr下降速度显著高于抗高血压治疗血压控制良好患者(P<0.01);前者需转透析百分比显著高于后者(P<0.01);进入ESRD的平均时间明显短于后者(P<0.01)。提示:高血压加速了CRF的进展,抗高血压治疗有延缓CRF进展速度的作用。
Analyze the average monthly increase of serum creatinine (Scr) and mean monthly rate of endogenous creatinine clearance (Ccr) in 42 patients with chronic renal insufficiency (CRF) accompanied by hypertension; mean time to enter end-stage renal disease (ESRD) Turn dialysis treatment percentage. The results showed that the mean monthly Scr rise and Ccr decrease rate in patients with poor blood pressure control were significantly higher than those in patients with well-controlled blood pressure control (P <0.01); the former need to dialysis percentage was significantly higher than the latter (P <0.01) The mean duration of ESRD was significantly shorter than the latter (P <0.01). Hint: Hypertension has accelerated the progression of CRF and antihypertensive treatment has the effect of slowing the progression of CRF.