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本文旨在复习引起胎儿畸形的各种因素及药物的影响。动物实验虽可用于指导用药,但不一定提示人类用药的结果。不同种族对某一药物的致畸易感性不同。同种不同族的易感性也不相同。另外,估价某一药物的致畸作用意义时,必须根据在群体中畸形的发生率来衡量,才能比较容易地确定各种药物引起畸形的多少。
This article aims to review the various factors that cause fetal malformations and the effects of drugs. Although animal experiments can be used to guide the medication, but does not necessarily prompt the results of human medication. Different ethnic groups have different teratogenic susceptibility to certain drugs. The same kind of different ethnic groups are not the same. In addition, the evaluation of the teratogenic effect of a drug, it must be based on the incidence of deformity in the population to be measured in order to more easily determine the number of malformations caused by various drugs.