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闭锁综合征是指有四肢瘫,末组运动颅神经麻痹和意识清楚的病人。病人用眨眼和眼球运动来表示自己意志的能力,其病变在桥脑腹侧部。作者报告一例经病理证实的急性炎症性多发性神经根神经病病人出现闭锁综合征。患者、女、45岁。既往健康,在不明原因发热后出现双下肢肌肉痛。几天后,迅速出现四肢和胸部肌肉进行性无力,两天后四肢轻瘫,伴有吞咽和呼吸困难。入院后及时进行辅助呼吸。神经系检查:四肢和由桥脑延髓神经所支配的肌肉完全瘫痪。病人意识清楚,眼球能向各方运动,瞳孔中等大,对光反应迅速。常规实验室检查无异常。脑电图正常。
Atresia syndrome refers to the four limbs paralysis, the last group of cranial nerve paralysis and consciousness of patients. The patient’s ability to express his or her own will with blinking and eye movements, the lesion in the ventral pontine. The authors report a case of atresia syndrome in a patient with pathologically confirmed acute inflammatory multiple nerve root neuropathy. Patient, female, 45 years old. Past health, fever in unknown causes of lower extremity muscle pain. A few days later, the limbs and chest muscles rapidly developed progressive weakness. After two days, the limbs were slightly paralyzed with swallowing and breathing difficulties. Auxiliary breathing promptly after admission. Nervous system examination: The limbs and the muscles dominated by the medulla oblongata nerve are completely paralyzed. Clear awareness of the patient, the eye can move to all parties, the pupil is medium large, rapid response to light. No abnormalities in routine laboratory tests. EEG normal.