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目的方法 :用S 10 0蛋白抗体 ,ABC免疫酶标法对 91例食管癌组织内S 10 0阳性树突状细胞进行定量观察 ,并与临床病理资料及随访结果对比分析。结果 :表明术后生存期≥ 5年者癌组织S 10 0阳性树突状细胞数量明显高于术后生存期 <5年者 (P <0 .0 1)。在具有同一种病理因素的患者中 ,生存期不同者其癌组织树突状细胞数量差异有显著性。提示 :癌组织内树突状细胞数量可作为估计患者预后的指标之一。
Objective: To investigate the expression of S 10 0 positive dendritic cells in 91 cases of esophageal carcinoma with S 10 0 antibody and ABC immunohistochemical method, and to compare with clinicopathological data and follow-up results. Results: The number of S 10 0-positive dendritic cells in cancer tissues with a survival time of 5 years or more was significantly higher than those with survival of less than 5 years (P <0.01). In patients with the same pathological factors, the difference in the number of dendritic cells in cancer tissues was significant. Tip: The number of dendritic cells in cancer tissue can be used as one of the indicators to estimate the prognosis of patients.