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血管中心型淋巴瘤为一种外周T细胞淋巴瘤的新亚型。本文报告2例并进行病理形态及免疫组化的研究。2例均表现为全身淋巴结肿大,例1尚表现为肝、脾肿大及胸腹部皮肤弥漫性红色丘疹。淋巴结活检最显著的特征是瘤细胞广泛浸润血管壁并可围绕血管呈洋葱皮样。免疫组化检测提示为外周T细胞淋巴瘤。本文尚对本病的命名、诊断标准及鉴别诊断等进行了初步探讨。
Vascular central lymphoma is a new subtype of peripheral T cell lymphoma. This article reports 2 cases and pathological morphology and immunohistochemistry research. 2 cases showed generalized lymphadenopathy, case 1 is still manifested as liver, splenomegaly and chest and abdomen skin diffuse red papules. The most striking feature of lymph node biopsy is that the tumor cells extensively infiltrate the blood vessel wall and can be onion-like around the blood vessel. Immunohistochemical detection prompted peripheral T cell lymphoma. This article still on the naming of the disease, diagnostic criteria and differential diagnosis were discussed.