充胀左心房时,一方面刺激心房容量感受器,反射地抑制升压素及肾素分泌,抑制肾神经活动,使尿量和尿钠增加;另一方面引起心房钠尿因子(atrial natriuretic factor,ANF)释放增多。ANF可能间接地通过与其他神经或/和体液机制的相互作用,引起利尿和钠尿效应。本文从升压素、血管紧张素、ANF及其相互关系几方面,阐述充胀左心房引起肾效应的体液机制。 Inflation of the left atrium, on the one hand to stimulate the atrial volume receptors, reflex inhibition of vasopressin and renin secretion, inhibition of renal nerve activity, so that urine output and urinary sodium increased; on the other hand cause atrial natriuretic factor (atrial natriuretic factor, ANF) increased release. ANF ​​may cause diuretic and natriuretic effects indirectly through interactions with other neural and / or humoral mechanisms. This article describes the body fluid mechanism that causes the left atrium to cause a kidney effect from the aspects of the vasopressin, angiotensin, ANF and their interrelations.