论文部分内容阅读
目的：动态观测急性脑梗死患者血浆内皮素含量变化，以探讨脑梗死与内皮素含量的关系。方法：用放射免疫法对４２例脑梗死患者血浆内皮素含量进行测定及分析比较。结果：发现脑梗死患者一周内血浆内皮素浓度明显增高，３周后下降，且大面积梗死者高于一般梗死，伴有高血压或糖尿病者高于单纯梗死者。结论：内皮素含量可间接反映病情及预后，故对脑梗死及早应用钙通道阻滞剂及内皮素抗体，益于病情恢复。
Objective: To dynamically observe the change of plasma endothelin concentration in patients with acute cerebral infarction and to explore the relationship between cerebral infarction and endothelin content. Methods: The plasma levels of endothelin in 42 patients with cerebral infarction were determined by radioimmunoassay. Results: The concentration of plasma endothelin was significantly increased in patients with cerebral infarction within one week and decreased after 3 weeks. The infarct size was higher in infarcted patients than in normal infarcts, with hypertension or diabetes mellitus being higher than those with infarct. Conclusion: Endothelin content can indirectly reflect the disease and prognosis, so the early application of calcium channel blockers and endothelin antibodies to cerebral infarction, benefit recovery.