一“朱砂畏磁石,恶咸水”一语,始出晋《吴普本草》,该书约成于公元二世纪,为较早的药物学专著。按《神农本草经》七情所规定的意义,其本意当指磁石能减轻或消除朱砂的毒性,而咸水则可能使朱砂的疗效降低或丧失。此后不久,齐·徐之才在另一药物学著作“药对”中载:“朱砂恶磁 A phrase of ”Crismus, magnetite, brackish water,“ began to appear in Jin Pu’s ”Wu Pu Materia Medica.“ This book was written in the second century AD and is an earlier monograph on pharmacology. According to the meaning provided by the “Shen Nong Ben Cao Jing” seven emotions, its original intention is to refer to a magnet that can reduce or eliminate the toxicity of cinnabar, and salt water may reduce or lose the efficacy of cinnabar. Soon afterwards, Qi Xu’s ability to contain in another pharmacological book ”Pharmaceutical Pairs“: ”Chusha Eccentrography