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目的:观察乙型肝炎表面抗体阳性血浆治疗重型乙型肝炎的安全性和临床疗效。方法:对68例重型乙型肝炎患者在综合治疗基础上分别采用乙型肝炎表面抗体阳性和阴性血浆治疗,观察不良反应和好转率。结果:两组不良反应发生率无统计学差异(P>0.05)。表面抗体阳性组好转出院25例(67.57%);阴性组好转出院17例(54.84%),好转率无统计学差异(P>0.05)。结论:乙型肝炎表面抗体阳性血浆治疗重型乙型肝炎安全、有效。
Objective: To observe the safety and clinical efficacy of hepatitis B surface antigen-positive plasma in the treatment of severe hepatitis B. Methods: Sixty-eight patients with severe hepatitis B were treated with HBsAg-positive and -negative plasma on the basis of comprehensive treatment, and the adverse reaction and improvement rate were observed. Results: There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). There were 25 patients (67.57%) in the positive antibody group and 17 patients (54.84%) in the negative antibody group. There was no significant difference in improvement rate (P> 0.05). Conclusion: Hepatitis B surface antibody-positive plasma is safe and effective in the treatment of severe hepatitis B.