论文部分内容阅读
染色体变异可能有的表现型作用问题至今仍未解决。有两种假说:一、变异完全没有表现型的作用。他们全是“正常的”,即选择中性的,可能仅包含“废弃”的DNA。二、变异有选择的涵义。他们能够影响携带者(以有利或不利的方式)或能造成携带者较为脆弱,因此有间接表现型的作用。为了测验某些变异可以影响智力特性的假说,作者对100例原发性智力迟缓男性病人的Q带与C带染色体与对照组皇家军事学院100例学员进行比较。9qh(9号染色体副缢痕)大小的增加,看来可能具有反面作用的因素。9qh-(9号染色体长臂副缢痕大小减少)在对照标本中较为常见。在智力迟缓人群中较常发现的另一个变异是16qh~-。在智
The possible phenotypic role of chromosomal aberrations remains unresolved. There are two kinds of hypotheses: First, there is no phenotypic effect at all. They are all “normal”, that is, they choose neutral and may only contain “discarded” DNA. Second, the meaning of variation has a choice. They can affect the carrier (in a beneficial or unfavorable way) or can make the carrier more vulnerable and therefore have an indirect phenotype. In order to test the hypothesis that certain mutations may affect IQ, the authors compared Q-banding with C-banding in 100 cases of primary mental retardation in men with 100 participants at RCS Royal Military Academy. An increase in the size of 9qh (chromosome 9) may appear to have the opposite effect. 9qh- (chromosome 9 long arm secondary scar size reduction) is more common in control specimens. Another common mutation found in people with mental retardation is 16qh ~ -. In wisdom