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我科1981年收治菌痢107例,成人63例,小儿44例;男69例,女38例;毒痢9例,急性菌痢98例;临床治愈95例,治疗好转因故出院12例.病人主要来自郑州及其郊区、郊县,也有一部分来自我省的其他17个市、县.现根据107例的初步分析,谈谈有关治疗中的几个问题.一、抗菌药物的选择:我科住院病人多系在外院治疗无效者.在细菌学检查未获结果前,最棘手的是抗菌药物的选择.由于痢疾杆菌对各种抗菌药物的耐药性逐年增加,造成投药困难.从107例粪培养阳性的药敏试验证明,绝大多数病例对氯霉素、四环素、土霉素、链霉素、多粘菌素,甚至增效磺胺(特指复方新明磺即 SMZCO 和复方消炎磺即 SMDCO,下同)均普遍耐药.因目前我国流行的菌群主要是福氏痢菌,本组粪培养阳性结果中
In 1981, our department treated 107 cases of bacillary dysentery, 63 adults and 44 children, including 69 males and 38 females, 9 cases of dysentery, 98 cases of acute bacillary dysentery, and 95 cases of clinical cure. Patients mainly from Zhengzhou and its suburbs, suburbs, but also from the province’s other 17 cities and counties.According to the preliminary analysis of 107 cases, to talk about the treatment of several issues .Antimicrobials choice: I Section inpatients and more outside the hospital treatment ineffective in bacteriological examination before the results, the most intractable is the choice of antimicrobial drugs due to dysentery bacilli for various antimicrobial resistance increased year by year, resulting in difficult to vote from 107 Case-positive culture susceptibility test proved that the vast majority of cases of chloramphenicol, tetracycline, oxytetracycline, streptomycin, polymyxin, and even synergistic sulfonamides (especially SMZCO compound compound anti-inflammatory and SMZCO Sulfo-SMDCO, the same below) are generally resistant .Because the prevailing flora in China is mainly Freunds’ bacillus, this group of fecal culture positive results