多西他奇（商品名Taxotere）为一种类似紫杉醇（paclitaxel）的半合成taxoid，美国FDA已批准其用于在意环类（如阿霉素）治疗期间仍处在进展或复发中的晚期或转移性乳腺癌患者。1药理学象紫杉醇一样，多西他奇也可结合游离的微管蛋白并促进稳定的微小管聚合，干扰有丝分裂和细 Docetaxel (trade name Taxotere) is a semi-synthetic taxoid that resembles paclitaxel, and the FDA has approved its use in advanced or relapsed stages of treatment with idiocycins such as doxorubicin or Metastatic breast cancer patients. 1 Pharmacology Like paclitaxel, docetaxel can also bind free tubulin and promote stable microtubule polymerization, interfering with mitosis and fine