恶性腹膜间皮瘤临床少见,术前诊断困难,极易误诊或漏诊。本文结合临床及文献复习对3例经手术和病理检查确诊的腹膜间皮瘤患者进行分析,以探讨本病的发病特点、临床表现、误诊原因及早期诊断等问题,并强调采用腹腔内化疗、腹部放疗和外科切除联合疗法,有助于提高疗效,延长患者的生存期。 Malignant peritoneal mesothelioma is rarely seen clinically. It is difficult to diagnose preoperatively and it is easily misdiagnosed or missed. In this paper, 3 cases of peritoneal mesothelioma diagnosed by surgery and pathological examination were analyzed in combination with clinical review and literature review to explore the characteristics of the disease, clinical manifestations, misdiagnosis reasons and early diagnosis and other issues, and emphasized the use of intraperitoneal chemotherapy, Abdominal radiotherapy and surgical resection combined therapy can help improve the efficacy and prolong the survival of patients.