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目的探讨新疆乌鲁木齐地区老年人群血脂、体质量指数(BMI)与骨质疏松的相关性。方法 200例老年患者根据骨质疏松的诊断标准分为骨质疏松组(105例)及非骨质疏松组(95例),记录两组患者一般情况,测量身高、血压、BMI、总胆固醇(TC)、高脂血症(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白-胆固醇(LDL-C),并进行相关性分析。结果老年女性骨质疏松比例明显高于老年男性,差异无统计学意义(P>0.05)。骨质疏松组BMI均较非骨质疏松组低(P<0.05),男性骨密度与BMI呈显著正相关,女性骨密度与BMI呈正相关,与TC、LDL-C呈负相关。Logistic回归分析结果显示,男性BMI是骨质疏松的独立危险因素,女性BMI及TC是骨质疏松的影响因素。结论老年患者BMI增加可能减少骨质疏松的发生,对老年女性进行适当的调脂治疗可能对预防老年女性骨质疏松有益。
Objective To investigate the relationship between serum lipids, body mass index (BMI) and osteoporosis in the elderly in Urumqi, Xinjiang. Methods 200 elderly patients were divided into osteoporosis group (n = 105) and non-osteoporosis group (n = 95) according to the diagnostic criteria of osteoporosis. The general conditions of two groups were recorded and their height, blood pressure, BMI and total cholesterol TC, HD, HDL-C and LDL-C were determined and analyzed. Results The proportion of osteoporosis in elderly women was significantly higher than that in the elderly men, the difference was not statistically significant (P> 0.05). The BMI in osteoporosis group was lower than that in non-osteoporosis group (P <0.05). There was a significant positive correlation between BMD and BMI in female. BMD was positively correlated with BMI and negatively correlated with TC and LDL-C. Logistic regression analysis showed that male BMI was an independent risk factor for osteoporosis. Female BMI and TC were the influencing factors of osteoporosis. Conclusion The increase of BMI in elderly patients may reduce the occurrence of osteoporosis. Appropriate lipid-lowering treatment of elderly women may be beneficial in preventing osteoporosis in elderly women.