烧伤后局部组织血管通透性的增加及严重烧伤后烧伤远离部位血管通透性的增加是引起组织水肿的病理基础。尽管目前对其发生机理还不甚了解,但很多学者认为可能与组织胺、5-羟色胺、慢反应物质、激肽、前列腺素和Thromboxane等有关。并应用上述各种介质的拮抗剂,如应用神经阻滞药物、烟酸、Venalot、Mepyranine、Indo-methacin、甲基强地松龙、潘生丁、利血平、H_2受体拮抗剂等对抑制伤后组织水肿进行了实验研究。近年来尤为引人注目的 The increase of vascular permeability of local tissue after burn and the increase of vascular permeability away from the site of severe burn after burn are the pathological basis of tissue edema. Although its mechanism is not well understood at present, many scholars think it may be related to histamine, serotonin, slow reacting substances, kinins, prostaglandins and Thromboxane. Antagonists such as nerve block drugs, niacin, Venalot, Mepyranine, Indo-methacin, methylprednisolone, dipyridamole, reserpine, H 2 receptor antagonists, Post-organizational edema was experimentally studied. Especially noticeable in recent years