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目的探讨二仙汤治疗围绝经期综合征的依据。方法利用10%围绝经期综合征大鼠血清培养正常大鼠的卵巢颗粒细胞以复制围绝经期综合征的细胞模型,观察二仙汤对该模型中卵巢颗粒细胞生长的影响。结果二仙汤对颗粒细胞的生长呈现促进作用。结论二仙汤在临床治疗围绝经期综合征与其对颗粒细胞生长的促进作用有关。
Objective To investigate the basis of Erxian decoction in treating perimenopausal syndrome. Methods Ovarian granulosa cells of normal rats were cultured in the serum of 10% climacteric syndrome rats to replicate the cell model of climacteric syndrome. The effect of Erxian decoction on the growth of ovarian granulosa cells in this model was observed. Results Erxian decoction on the growth of granulosa cells showed a role in promoting. Conclusion Erxian decoction in the treatment of perimenopausal syndrome and its role in promoting the growth of granulosa cells.