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目的：比较国产与进口蒙脱石（ｓｍｅｃｔｉｔｅ） 治疗小儿急性腹泻的疗效。方法：６２ 例急性腹泻病人随机分成国产蒙脱石组３０ 例（ 男性２２ 例，女性８ 例，年龄２１ ｍｏ ±ｓ１６ ｍｏ） 予国产蒙脱石治疗，进口蒙脱石组３２ 例（ 男性２２ 例，女性１０ 例，年龄２０ ｍｏ ±５ｍｏ） 予进口蒙脱石治疗，剂量均为：年龄＜ １ ａ 为３ｇ／ｄ ；１ ～２ ａ 为３ ～６ ｇ／ｄ ；２ ～３ ａ 为６ ～９ ｇ／ｄ ； ＞ ３ ａ为９ ｇ／ｄ ，分３ 次加温水５０ ｍ Ｌ 口服，疗程３ ｄ 。进行疗效观察，并观察不良反应。结果：国产蒙脱石组总有效率为９３ ％ ，与进口蒙脱石组（９４ ％ ） 比较，２ 组差别无显著意义（ Ｐ＞ ０ ．０５） 。不良反应小。结论：国产蒙脱石治疗小儿急性腹泻安全、有效，与进口蒙脱石相仿。
Objective: To compare the efficacy of domestic and imported smectite in the treatment of children with acute diarrhea. Methods: Thirty-two patients with acute diarrhea were randomly divided into domestic montmorillonite group (22 males and 8 females, 21 mo ± s16 mo) for domestic montmorillonite treatment, and 32 patients (22 males , 10 females, age 20 mo ± 5mo) to be imported montmorillonite, the dose were: age <1 a for the 3g / d; 1 ~ 2 a for 3 ~ 6 g / d; 2 ~ 3 a for 6 ~ 9 g / d;> 3 a for 9 g / d, divided into three warm water 50 m L orally, course of treatment 3 d. The efficacy of observation, and observe the adverse reactions. Results: The total effective rate of domestic montmorillonite group was 93%. Compared with imported montmorillonite group (94%), there was no significant difference between the two groups (P> 0.05). Adverse reactions are small. Conclusion: The domestic montmorillonite treatment of children with acute diarrhea safe and effective, similar to the imported montmorillonite.