论文部分内容阅读
目的:观察双水平气道正压通气治疗肥胖低通气综合征的临床效果。方法:16例肥胖低通气综合征患者应用双水平气道正压通气治疗,观察治疗前、后肺功能、血气分析及多导睡眠图变化。结果:治疗后第1秒用力呼气容积占预计值百分比、第1秒用力呼气容积/用力肺活量及肺总量占预计值百分比均高于治疗前,但差异无统计学意义(P>0.05)。治疗后动脉血氧分压、二氧化碳分压、氧饱和度、呼吸紊乱指数、低通气指数及最低氧饱和度均较治疗前改善(P<0.01)。结论:双水平气道正压通气治疗肥胖低通气综合征具有良好的临床效果。
Objective: To observe the clinical effect of bi-level positive airway pressure ventilation on obesity-hypoventilation syndrome. Methods: Sixteen patients with obesity and hypoventilation syndrome were treated with bi-level positive airway pressure. The changes of pulmonary function, blood gas analysis and polysomnography were observed before and after treatment. Results: The forced expiratory volume in the first second after treatment was a percentage of the predicted value, the forced expiratory volume / forced expiratory volume in one second and the percentage of predicted total lung volume were higher than before treatment, but the difference was not statistically significant (P> 0.05 ). After treatment, arterial partial pressure of oxygen, partial pressure of carbon dioxide, oxygen saturation, respiratory disturbance index, hypoglycaemia index and lowest oxygen saturation were all improved than those before treatment (P <0.01). Conclusion: Biphasic positive airway pressure ventilation has a good clinical effect in the treatment of obesity-hypoventilation syndrome.