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为探讨血清及肝脏HBV标志物的相关性及肝内HBAg存在状态与临床症征、生化指标及肝脏病理之间的关系,我们对21例不同类型乙肝患者进行了对比分析,报告如下。1 材料与方法1.1 病例选择及诊断标准:选1987年12月～1988年10月我院住院患者21例。年龄16～58岁,平均43±12岁;男性20例,女性1例。所有病例经皮肝穿活检。病理诊断和组织化学或免疫组织化学染色。病程在2周～11年。病理诊断参照1984年全国病毒性肝炎防治方案中组织学诊断标准。计急性肝炎(急肝)1例,慢性迁延性肝炎(慢迁肝)5例,慢性活动性肝炎(慢活肝)10例,肝硬化5例。肝穿前后1周内检测生化及乙肝血清学指标。
To investigate the correlation between serum and liver HBV markers and the relationship between the presence of intrahepatic HBAg and clinical signs, biochemical parameters and liver pathology, 21 cases of different types of hepatitis B patients were analyzed and compared as follows. 1 Materials and Methods 1.1 Case Selection and Diagnostic Criteria: Selected from December 1987 to October 1988 in our hospital 21 patients. Aged 16 to 58 years, mean 43 ± 12 years; 20 males and 1 females. All cases of percutaneous liver biopsy. Pathological diagnosis and histochemistry or immunohistochemical staining. Course of disease in 2 weeks to 11 years. Reference to the pathological diagnosis of the national program of prevention and treatment of viral hepatitis in 1984 diagnostic criteria. One case of acute hepatitis (acute liver), 5 cases of chronic persistent hepatitis (slow moving liver), 10 cases of chronic active hepatitis (slow living liver) and 5 cases of liver cirrhosis. Biochemical and Hepatitis B serological markers were detected within 1 week before and after liver perfusion.