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目的观察普米克、美喘清对儿童咳嗽变异型哮喘的治疗效果。方法 ３６例患儿均应用普米克和美喘清治疗。普米克气雾剂吸入：５０—１００ μｇ，每日 ３次，咳嗽控制后减量至 ５０ μｇ，每日 １次，疗程 ２月；美喘清在普米克吸入前半小时口服：＜７岁 １２ ５ μｇ，≥７岁 ２５ μｇ，每日 ２次，疗程 １５ ｄ，治疗结束后随访半年。对其中≥７岁者于治疗前，治疗后 １５ ｄ，１月，３月进行最高呼气流速率（ＰＥＦＲ）检测。结果 ３６例中的２９例在治疗 １５ ｄ内临床症状消失，５例在治疗３０ ｄ内咳嗽消失，１例咳嗽减轻，１例无效，随访 １例复发，总有效率９７．２２％（３５／３６），复发率２．７８％（１／３６）。与治疗前相比，ＰＥＦＲ在治疗后 １５ ｄ，１月，３月有明显改善， Ｐ分别＜０．０２，０．０２及０．０１。结论普米克、美喘清联用对儿童咳嗽变异型哮喘疗效满意，对肺功能有明显改善。
Objective To observe the therapeutic effect of Pulmicort and Mechuanqing on children with cough variant asthma. Methods Thirty-six children were treated with Pulmicort and Mechuanqing. Pulmicort aerosol inhalation: 50-100 μg, 3 times a day, cough control and then reduced to 50 μg, 1 day, course of treatment in February; melatonin clearance half an hour before Pulmicort inhalation Oral: <7 years old 12 5 μg, ≥ 7 years old 25 μg, twice daily for 15 days, followed up for six months after the end of treatment. The maximum expiratory flow rate (PEFR) was measured before treatment, 15 days after treatment, January and March after ≥7 years of age. Results Of the 36 cases, 29 cases disappeared within 15 days of treatment, 5 cases disappeared within 30 days of treatment, 1 case had cough relief, 1 case was ineffective and 1 case was followed up. The total effective rate was 97.22% (35 / 36), the recurrence rate was 2.78% (1/36). Compared with before treatment, PEFR at 15 d, January and March after treatment had a significant improvement, P <0.02, 0.02 and 0.01. Conclusion Pulmicort and Mi-chuan qinglian are effective in treating children with cough variant asthma and have obvious improvement on pulmonary function.