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血管内皮生长因子是血管生成的关键性因子,对于肿瘤生长,侵袭,转移发挥着重要作用。本文对其启动子序列上转录因子的结合与调控进行综述。
Vascular endothelial growth factor is a key factor of angiogenesis and plays an important role in tumor growth, invasion and metastasis. This review summarizes the binding and regulation of transcription factors in their promoter sequences.