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~(99m)Tc-HMPAO是一种良好的血细胞标记物,其特点与~(111)In-Oxine和~(111)In-troplone相似,显像结果也与之可比,而且标记过程很方便.因而它是一种很有前途的血栓显影剂.本文报道按Amersham公司说明书制备的~(99m)Tc-HMPAO标记血小板在体内外的研究结果.体外研究结果:①培养温度和时间:标记率的变化与培养温度及培养时间呈正比.最佳温度为37℃.在3~10分钟时,标记率增高最快;20~30
~ (99m) Tc-HMPAO is a good blood cell marker with similar characteristics to ~ (111) In-Oxine and ~ (111) In-troplone. The imaging results are also comparable. Therefore, it is a promising thrombus developer.This paper reports the results of in vitro and in vivo studies of ~ (99m) Tc-HMPAO labeled platelets prepared in accordance with the instructions of Amersham Company.In vitro study results: ① incubation temperature and time: labeling rate Changes and incubation temperature and incubation time is proportional to the best temperature of 37 ° C in 3 to 10 minutes, the fastest increase in labeling rate; 20 to 30