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目的探讨英夫利西单抗治疗类风湿关节炎的临床效果及护理。方法 86例类风湿关节炎患者,随机分为对照组和观察组,每组43例。两组患者均采用英夫利西单抗治疗,对照组采用一般护理,观察组采用针对性护理,对比两组患者肿胀和触痛关节计数改善达20%(ACR20)例数和不良反应发生率。结果治疗14周后观察组患者ACR20达标例数多于对照组,差异有统计学意义(P<0.05);观察组患者的不良反应发生率明显较对照组低,差异有统计学意义(P<0.05)。结论对类风湿关节炎患者采取积极主动的针对性护理,可以有效提高英夫利西单抗治疗类风湿关节炎的治疗效果,减少不良反应的发生。
Objective To investigate the clinical efficacy and nursing of infliximab in the treatment of rheumatoid arthritis. Methods A total of 86 patients with rheumatoid arthritis were randomly divided into control group and observation group, with 43 cases in each group. Both groups were treated with Infliximab, the control group were treated with general care, the observation group were treated with targeted care, compared with 20% (ACR20) number of cases of joint swelling and tenderness and the incidence of adverse reactions in both groups. Results After 14 weeks of treatment, the number of ACR20 cases in the observation group was more than that of the control group (P <0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group (P < 0.05). Conclusion Taking active and targeted care for patients with rheumatoid arthritis can effectively improve the therapeutic effect of infliximab in the treatment of rheumatoid arthritis and reduce the incidence of adverse reactions.