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本文报道使用国产巯甲丙脯酸及合并利尿剂治疗轻、中型高血压的短期临床观察。表明在普通饮食条件下单用巯甲丙脯酸降压疗效并不理想,总有效率41.4％;合并利尿剂后的疗效与降压幅度明显提高,总有效率上升为78.0％,约有1/4患者出现副作用。因此,巯甲丙脯酸合并利尿剂是一个有效而合理的高血压治疗方案,但不宜作为首选药物,也不宜使用大剂量。
This article reports the use of domestic captopril and diuretics in the treatment of light and medium-term hypertension in short-term clinical observation. The results showed that the antihypertensive effect of captopril alone was not satisfactory under general dietary conditions, with a total effective rate of 41.4%. The curative effect and antihypertensive rate after diuretics were significantly increased, with the total effective rate increasing to 78.0%, about 1 / 4 patients with side effects. Therefore, captopril combined diuretics is an effective and reasonable treatment of hypertension, but not as the preferred drug, it is not appropriate to use large doses.