对于将环葡萄糖(Cyclodextrin)作为包结宿主用于酶模型和反应环境的研究,已进行了很多工作。在这些工作中,环葡萄糖的内穴尺寸和高度均为固定,在包结过程中构象也基本保持不变。可是生物化学的研究已经肯定了酶分子的构象变化在生物过程中的重要性,因此在用物理有机化学方法研究酶的模型反应时也必须考虑这一因素。本文报导了具有类似环葡萄糖疏水内穴特性,而分子长度及内穴尺寸均 Much work has been done on the use of Cyclodextrin as an entrapment host for the study of enzyme models and the reaction environment. In these tasks, the size and height of the inner cavity of the ring glucose are fixed, the conformation in the process of inclusion is basically unchanged. However, biochemical studies have confirmed the importance of conformational changes in enzyme molecules in biological processes and therefore must be considered when studying the model reactions of enzymes using physico-chemical methods. In this paper, we report the hydrophobic cavity-like features of cyclodextrins, while both the molecular length and the size of the internal cavities