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目的:探讨低分子肝素(LMWH)联合百令胶囊对原发性肾病综合征(PNS)的临床疗效。方法:将临床确诊108例PNS病例随机分为对照组36例(常规激素治疗);LMWH组38例(常规激素加用LMWH);治疗组34例(在常规激素基础上加用LMWH联合百令胶囊)。检测治疗前后各组24h Upro、Alb、Tc、Scr,BUN、PT、Plt变化。结果:治疗8周后,治疗组治疗前后24hUpro、Tc显著降低。Alb显著升高(P<0.01),且明显优于对照组(P<0.01)及LMWH组(P<0.05)。结论:在激素基础上加用LMWH联合百令胶囊治疗PNS能更有效地提高疗效,改善预后。
Objective: To investigate the clinical effect of low molecular weight heparin (LMWH) combined with Bailing capsule on primary nephrotic syndrome (PNS). Methods: One hundred and eighty patients with PNS were randomly divided into control group (n = 36) and conventional LMWH group (n = 38). The treatment group (n = 34) capsule). The levels of Upro, Alb, Tc, Scr, BUN, PT and Plt in each group were measured before and after treatment. Results: After 8 weeks of treatment, 24hUpro and Tc in the treatment group decreased significantly before and after treatment. Alb significantly increased (P <0.01), and was significantly better than the control group (P <0.01) and LMWH group (P <0.05). Conclusion: The addition of LMWH combined with Bailing capsule on the basis of hormones in the treatment of PNS can effectively improve the curative effect and improve the prognosis.