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目的:探讨并分析肾细胞癌术后放疗价值及治疗失败原因。方法:1988年1月~1992年3月收治43例肾细胞癌术后病人,单纯手术22例,手术加术后放疗21例,放疗剂量50Gy/SW左右。结果:单纯手术者五年生存率为43.5%,手术加术后放疗者五年生存率为47.6%,两者比较无明显差异(P>0.05)。单纯手术组死于远地转移者占66.7%(10/15,除外Ⅳb期7例),手术加术后放疗组死于远地转移者占66.7%(14/21),两者无显著差异(P>0.05)。结论:远地转移为肾细胞癌治疗失败的主要原因,需寻找新的综合治疗手段解决远地转移问题。
Objective: To investigate and analyze the value of postoperative radiotherapy for renal cell carcinoma and the causes of treatment failure. Methods: From January 1988 to March 1992, 43 patients with postoperative renal cell carcinoma were treated. Twenty-two patients underwent surgery alone, and 21 patients underwent surgery plus postoperative radiotherapy. The radiation dose was about 50 Gy/SW. Results: The five-year survival rate was 43.5% in patients undergoing surgery alone, and 47.6% in patients undergoing surgery plus postoperative radiotherapy. There was no significant difference between the two groups (P>0.05). 66.7% (10/15, except for IVb) of 66.7% (14/21) died of distant metastases in the surgery alone group, and 66.7% (14/21) of the patients died of distant metastases after surgery and postoperative radiotherapy. There was no significant difference (P>0.05). Conclusion: The distant metastasis is the main reason for the failure of renal cell carcinoma. It is necessary to find a new comprehensive treatment to resolve the problem of distant metastasis.