胃泌素(gastrin)是刺激胃腺壁细胞分泌胃酸的一种重要的胃肠道激素,其分子结构与胆囊收缩素(CCK)相似,壁细胞上胃泌素受体的药理学特性与脑内CCK受体(CCK-B受体)非常相似,然而,胃泌素受体与CCK-B受体基因一直没有得到克隆,因此,要区别这两种受体十分困难。最近,美国学者Kopin等用放射配体结合 Gastrin is an important gastrointestinal hormone that stimulates gastric glandular cells to secrete gastric acid. Its molecular structure is similar to that of cholecystokinin (CCK). The pharmacological properties of gastrin receptors on parietal cells are similar to those of brain CCK receptors (CCK-B receptors) are very similar. However, there has been no cloning of gastrin receptors and CCK-B receptor genes. Therefore, it is very difficult to differentiate these two receptors. Recently, Kopin et al., A U.S. scholar, used radioligands to bind