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目的:比较分析青年与老年胃癌临床病理学特点,为临床诊断提供依据。方法:选取某医院数据库中1998年1月-2008年1月青年胃癌136例及老年胃癌200例按肿瘤部位、组织学类型、浸润深度、TNM分期、生长方式及转移等情况进行比较分析。结果:青年胃癌男女比例为2:1,以胃窦部及胃体部居多,病程平均9个月,肿瘤最大径≥5cm57例,组织学中分化18例,低分化29例;老年胃癌男女比例为3:1,以胃体部及贲门多见,病程平均16个月,肿瘤最大径≥5cm159例,组织学中分化89例,低分化18例。结论:青年胃癌恶性程度高、浸润能力强、病程较短、预后差,老年胃癌恶性程度低、浸润能力弱、病程虽长但预后较好。
Objective: To comparatively analyze the clinicopathological characteristics of young and old gastric cancer and provide the basis for clinical diagnosis. Methods: A hospital database of 136 cases of gastric cancer from January 1998 to January 2008 and 200 cases of elderly patients with gastric cancer by tumor location, histological type, depth of invasion, TNM staging, growth patterns and metastasis were compared. Results: The ratio of male to female in gastric cancer was 2: 1 in young patients, mostly in gastric antrum and gastric body. The average course of disease was 9 months. The maximum diameter of tumors was ≥5cm in 57 cases. The histological differentiation was in 18 cases and the poorly differentiated in 29 cases. 3: 1, with gastric body and cardia more common, duration of an average of 16 months, tumor diameter ≥ 5cm159 cases, histological differentiation in 89 cases, 18 cases of poorly differentiated. Conclusions: The young patients with gastric cancer have a high degree of malignancy, strong infiltration ability, short course of disease, poor prognosis, low malignant degree of gastric cancer and infiltrative ability. The long course of the disease has a good prognosis.