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采用ＡＦＢ１致大鼠肝癌作用的短期模型，探讨了广西肝癌高发区饮用塘水的致肝癌作用，结果发现：分别用０．２％塘水浓缩物和塘水富集物喂养的两组大鼠，其γ－谷氨酰转肽酶、三磷酸腺苷酶和葡萄糖－６－磷酸酶等三种癌前酶变灶的数量（灶／ｃｍ２，灶／ｃｍ３）均显著高于对照组，显示了明显诱发大鼠肝癌前病变的作用，提示广西肝癌高发区居民饮用的塘水中，可能存在与肝癌相关的致癌物。但本实验未发现塘水与ＡＦＢ＿１两因素间有协同致肝癌作用。
A short-term model of AFB1-induced liver cancer in rats was used to investigate the hepatocarcinogenic effects of drinking water from a high incidence area of Guangxi liver cancer. The results showed that two groups of rats fed with 0.2% pond water concentrate and pond water enrichment respectively The number of three precancerous changes of γ-glutamyl transpeptidase, adenosine triphosphatase and glucose-6-phosphatase (foci/cm2, foci/cm3) was significantly higher than that of the control group, indicating significant induction. The role of precancerous lesions in rats suggests that there may be carcinogens associated with liver cancer in the pond waters consumed by residents of high incidence areas in Guangxi. However, this experiment did not find that there was a synergistic liver cancer effect between Tangshui and AFB_1.