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A组轮状病毒是导致全球婴幼儿重症腹泻的最主要病因,其疾病负担巨大。已有研究证实,卫生状况的改善对轮状病毒腹泻的控制效果甚微,疫苗则是控制轮状病毒腹泻最有效的公共卫生干预措施。目前3种轮状病毒疫苗已在全球100多个国家及地区投入使用,并纳入部分国家的儿童计划免疫程序。本文简要综述人A组轮状病毒疫苗的研究进展,以期对我国轮状病毒疫苗的使用和推广提供借鉴。
A group of rotavirus is the leading cause of severe diarrhea in infants and children around the world, its disease burden. Studies have confirmed that the improvement of health conditions has little effect on the control of rotavirus diarrhea, and the vaccine is the most effective public health intervention to control rotavirus diarrhea. At present, three kinds of rotavirus vaccines have been put into use in over 100 countries and regions in the world and are included in the child immunization program of some countries. This article briefly reviews the research progress of human A group rotavirus vaccine in order to provide reference for the use and promotion of our country rotavirus vaccine.