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化合物Ⅱ在三氟化硼一乙醚催化下进行F.C反应时,除得到正常产物皿外,还分离出另一化合物Ⅳ,经鉴定为Ⅲ的脱溴产物,质谱分析M~+258,熔点与文献(2)相同.对于该脱溴反应尚不明了其机制,化合物Ⅵ与Ⅲ的比例约1:4.化合物Ⅲ的脱甲氧基反应是用三溴化硼在乙腈中进行,三溴化硼用量需加大至1:10(mol).反应温度为-10℃,环合之后的异黄酮类化合物脱甲氧基十分困难,先环合而后脱甲氧基未获成功.Ⅲ的环
When compound Ⅱ was catalyzed by boron trifluoride monoethylether, the product of normal reaction was removed and another compound Ⅳ was isolated. The product was identified as Ⅲ debromination product. M ~ + 258 was identified by mass spectrometry (2) is the same for the debromination reaction is not clear its mechanism, the ratio of compound VI and III is about 1: 4. The demethoxy reaction of compound III is carried out using boron tribromide in acetonitrile, boron tribromide The dosage should be increased to 1:10 (mol) .The reaction temperature is -10 ℃, the cyclodextrin is very difficult to demethoxy group after the first cyclization demethoxy was not successful. Ⅲ ring