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目的研究银杏叶提取物对老龄前期小鼠学习记忆能力的影响。方法以东茛菪碱和亚硝酸钠造成小鼠记忆缺失模型，跳台法进行行为检测。结果银杏叶提取物５０～１００ｍｇｋｇ－１，ｉｇ，ｑｄ×２１天能明显增强正常老龄前期小鼠的学习记忆能力，且对东茛菪碱、亚硝酸钠造成的记忆获得、巩固障碍有不同程度的改善作用。结论银杏叶提取物对老龄前期小鼠的学习记忆功能具有明显的促进作用
Objective To study the effects of Ginkgo biloba extract on learning and memory in presenile mice. Methods The scopolamine and sodium nitrite caused mice’s memory deficit model and the method of step-by-step detection. RESULTS: Ginkgo biloba extract 50-100 mg kg-1, ig, qd x 21 days could significantly enhance the learning and memory abilities of the mice in the normal old age and had different degrees of memory acquisition and consolidation obstacles caused by scopolamine and sodium nitrite. The improvement effect. Conclusion Ginkgo biloba extract has obvious promoting effect on the learning and memory function of presenile mice.