论文部分内容阅读
目的:自身免疫性肝病的发病机理至今尚未明确,与多种疾病之间存在着联系,临床诊断具有一定的难度。本研究利用超声弹性成像技术定量分析自身免疫性肝病的病理特征,探讨该技术的诊断价值,为自身免疫性疾病的治疗提供诊断依据。方法:选取我院2011年3月-2013年6月收治的自身免疫性肝病患者182例,随机分为观察组和对照组。观察组98例患者采用弹性成像定量分析的方法进行诊断,对照组84例则采用常规病理学诊断。观察并比较两组患者的诊断准确率及诊断耗时。结果:观察组检出94例,诊断率为95.92%;对照组检出81例,诊断率为96.43%,两组诊断准确率比较无明显差异(P>0.05)。观察组平均诊断耗时为5.6 h;对照组平均诊断耗时为11.6 h,观察组诊断时间比对照组短,差异具有统计学意义(P<0.05)。结论:弹性成像定量分析对自身免疫性肝病的诊断准确率与病理活检诊断具有较好的一致性,且诊断耗时短、患者依从性好,值得在临床中进一步推广应用以辅助病理诊断,避免误诊或漏诊现象发生。
OBJECTIVE: The pathogenesis of autoimmune liver disease is still unclear so far. It is associated with various diseases, and clinical diagnosis has some difficulties. In this study, the use of ultrasound elastography quantitative analysis of pathological features of autoimmune liver disease to explore the diagnostic value of the technology for the diagnosis of autoimmune diseases provide a diagnosis basis. Methods: A total of 182 patients with autoimmune liver disease admitted to our hospital from March 2011 to June 2013 were randomly divided into observation group and control group. Ninety-eight patients in the observation group were diagnosed by elastography quantitative analysis, and 84 patients in the control group were diagnosed by routine pathology. Observe and compare the diagnostic accuracy and time-consuming diagnosis of the two groups of patients. Results: In the observation group, 94 cases were detected, the diagnostic rate was 95.92%. In the control group, 81 cases were detected, the diagnostic rate was 96.43%. There was no significant difference between the two groups (P> 0.05). The average time of diagnosis in the observation group was 5.6 h. The mean time of diagnosis in the control group was 11.6 h. The diagnosis time in the observation group was shorter than that in the control group. The difference was statistically significant (P <0.05). Conclusion: The diagnostic accuracy of elastography quantitative analysis of autoimmune liver disease and pathological biopsy have good consistency, and the diagnosis of time-consuming short, patients with good compliance, it is worth further promotion in clinical application of pathological diagnosis, to avoid Misdiagnosis or missed diagnosis occurs.